I've received and reviewed the config information. For the benefit of the group, I'll post a summary so far.
- Check your server host BIOS power profile settings to make sure all hosts are set to "Maximum Performance". This is the cause of 90% of the storage "performance issues" I have seen in the past.
- Looking at the MSA config itself, it looks pretty good. Everything looks healthy and you've done a good job keeping your RAID set sizes identical and to a power of 2.
- One thing you have done, which is not best practice, is that you have 10 and 15k disks in the same pools and they are different sizes.
- The disks in your 15k vdisks are totally full (as would be expected), the 10K pools have an even amount of space which is good and means they are balancing out
- This will cause all new writes to go only to the larger 10k disks. Reads will be unpredictable. Older data will come from both the 15k and 10k disks, newer data may only come from the 10k disks. While this isn't best practice, I'm not sure it's the cause of your issue. I would lean towards host power profile settings, zoning, or multipathing issues. Please check those items.