It's not easy to design your setup with this much details.
Most important is wht type of application that you are going to execute. Next thing all 4 hosts will be in cluster or they will be individually take care one application.
If all 4 hosts taking care one application then I would suggest to create single Pool and create VDG with all 8 drives under this.
If you have multiple applications to handle then better to create two Pools and create 4 drive VDG per Pool. Let each pool takes care of application.
Hope this helps!
Regards
Subhajit
I am an HPE employee
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